Good and suitable resistance to temperature shock
Different dosage forms of medicines are required to undergo high-temperature drying, disinfection and sterilization or low-temperature freeze-drying and other processes in the production, which requires the glass container to have a good and suitable ability to resist sudden changes in temperature without bursting. The resistance to thermal shock of glass is mainly related to the coefficient of thermal expansion. The lower the coefficient of thermal expansion, the stronger the ability to resist temperature changes. For example, many high-grade vaccine preparations, biological preparations and lyophilized preparations should generally use 3.3 borosilicate glass or 5.0 borosilicate glass. When the low borosilicate glass produced in large quantities in China is subjected to a large temperature difference, it is often prone to bursting and the bottom of the bottle falling off. China's 3.3 borosilicate glass has great development, this glass is especially suitable for freeze-dried preparations, because its resistance to temperature shock is better than 5.0 borosilicate glass.
